Package index • DiAna

Setup

Functions to download cleaned FAERS data from the internet and snippet to automatically structure a script.

setup_DiAna(): Set Up DiAna Environment

snippets_install_github(): Install RStudio Snippets from GitHub Repository

Datasets

Datasets made available with the DiAna package.

Sample datasets with documentation

sample_Demo: Sample Demographic Data

sample_Demo_Supp: Sample Supplementary Demographic Data

sample_Doses: Sample Data on Drug Doses

sample_Drug: Sample Data on Drug Administration

sample_Drug_Name: Sample Data on Drug Names before standardization

sample_Drug_Supp: Sample Supplementary Drug Information

sample_Indi: Sample dataset containing indications for using reported drugs.

sample_Outc: Sample Data on Individual Outcomes

sample_Reac: Sample dataset containing events (suspected adverse drug reactions) and related information.

sample_Ther: Sample Data on Therapy Details

Importing fuctions for the full downloaded FAERS data

import(): import

import_ATC(): Import ATC classification

import_MedDRA(): Import MedDRA Data

Additional datasets provided for internal use by functions

country_dictionary: Country Dictionary Dataset

Case retrieval

Functions to retrieve cases or specific subpopulations.

Retrieve cases for manual inspection

retrieve(): Retrieve data for specific primaryids

Tailor drug definition

get_drugnames(): Retrieve Drug Names from FAERS Database

Fix_DiAna_dictionary_locally(): Fix DiAna Dictionary Locally

Identify specific subpopulations

retrieve_pregnancy_pids(): Retrieve Pregnancy-Related Report Identifiers from FAERS

Descriptive functions

Functions to perform descriptive analyses.

descriptive(): Generate Descriptive Statistics for a Sample

hierarchycal_rates(): Generate Hierarchy of events or substances

reporting_rates(): Reporting rates of events or substances

render_tto(): TTO Render Forest Plot

Disproportionality functions

Functions to perform disproportionality analyses.

disproportionality_analysis(): Perform Disproportionality Analysis

disproportionality_comparison(): Disproportionality Analysis for Drug-Event Combinations

disproportionality_trend(): Disproportionality Time Trend for a Drug-Event Combination

format_input_disproportionality(): Format Input for Disproportionality Analysis

tailor_disproportionality_threshold(): Tailor Disproportionality Threshold

plot_disproportionality_trend(): Plot Disproportionality Trend

render_forest(): Render Forest Plot

Advanced analyses

Functions to perform advanced analyses, including time to onset analysis and network analysis.

Time to onset analyses

time_to_onset_analysis(): Perform time-to-onset analysis for drug-event associations

plot_KS(): Plot Kolmogorov-Smirnov (KS) plot

Network Analysis

network_analysis(): Perform Network Analysis and Visualization

DiAna specifics

Functions to retrieve DiAna reference and information about the used quarter.

DiAna_reference(): Get DiAna reference

FAERS_quarter_specifics(): Get specifics of dictionaries used in database version