Package index

Setup

Functions to download cleaned FAERS data from the internet and snippet to automatically structure a script.

setup_DiAna()

Set Up DiAna Environment

snippets_install_github()

Install RStudio Snippets from GitHub Repository

Datasets

Datasets made available with the DiAna package.

Sample datasets with documentation

sample_Demo

Sample Demographic Data

sample_Demo_Supp

Sample Supplementary Demographic Data

sample_Doses

Sample Data on Drug Doses

sample_Drug

Sample Data on Drug Administration

sample_Drug_Name

Sample Data on Drug Names before standardization

sample_Drug_Supp

Sample Supplementary Drug Information

sample_Indi

Sample dataset containing indications for using reported drugs.

sample_Outc

Sample Data on Individual Outcomes

sample_Reac

Sample dataset containing events (suspected adverse drug reactions) and related information.

sample_Ther

Sample Data on Therapy Details

Importing fuctions for the full downloaded FAERS data

import()

import

import_ATC()

Import ATC classification

import_MedDRA()

Import MedDRA Data

extractSMQ()

Extract Standardised MedDRA Queries (SMQs)

Additional datasets provided for internal use by functions

country_dictionary

Country Dictionary Dataset

Case retrieval

Functions to retrieve cases or specific subpopulations.

Retrieve cases for manual inspection

retrieve()

Retrieve data for specific primaryids

Tailor drug definition

get_drugnames()

Retrieve Drug Names from FAERS Database

Fix_DiAna_dictionary_locally()

Fix DiAna Dictionary Locally

Identify specific subpopulations

retrieve_pregnancy_pids()

Retrieve Pregnancy-Related Report Identifiers from FAERS

Descriptive functions

Functions to perform descriptive analyses.

descriptive()

Generate Descriptive Statistics for a Sample

new_descriptive()

Generate Descriptive Statistics for a Sample

hierarchycal_rates()

Generate Hierarchy of events or substances

reporting_rates()

Reporting rates of events or substances

render_tto()

TTO Render Forest Plot

Disproportionality functions

Functions to perform disproportionality analyses.

disproportionality_analysis()

Perform Disproportionality Analysis

disproportionality_comparison()

Disproportionality Analysis for Drug-Event Combinations

disproportionality_trend()

Disproportionality Time Trend for a Drug-Event Combination

format_input_disproportionality()

Format Input for Disproportionality Analysis

tailor_disproportionality_threshold()

Tailor Disproportionality Threshold

plot_disproportionality_trend()

Plot Disproportionality Trend

render_forest()

Render Forest Plot

render_forest_table()

Render a Forest Plot Table from Disproportionality Data

Advanced analyses

Functions to perform advanced analyses, including time to onset analysis and network analysis.

Time to onset analyses

time_to_onset_analysis()

Perform time-to-onset analysis for drug-event associations

plot_KS()

Plot Kolmogorov-Smirnov (KS) plot

Network Analysis

network_analysis()

Perform Network Analysis and Visualization

DiAna specifics

Functions to retrieve DiAna reference and information about the used quarter.

DiAna_reference()

Get DiAna reference

FAERS_quarter_specifics()

Get specifics of dictionaries used in database version